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Future prospects and uses of dihydrocaffeic acid

2018-01-08 11:28
  Dihydrocaffeic acid, also known as 3,4-dihydroxyphenylpropionic acid, is a white crystalline powder that is soluble in organic solvents such as methanol, ethanol, and DMSO. longituba, has strong antioxidant activity.
 
In a study published online in the journal Nature Communications, scientists described an extensive analysis of new grape-derived compounds, dihydrocaffeic acid (DHCA), and sunflower pigment 3-O-glucoside ( Mal-gluc), which may be a cure for depression. The findings suggest that these natural compounds can attenuate depression by targeting newly discovered potential mechanisms.
 
The researchers found that DHCA and Mal-gluc can promote the resilience of depression model in mice by regulating inflammation and synaptic plasticity. DHCA reduces interleukin 6 (IL-6), a pro-inflammatory substance secreted by T cells and macrophages, which stimulates the immune response by phenotyping the non-coding sequences of the IL-6 gene. Mal-gluc regulates the histone acetylation of the Rac1 gene and allows transcriptional activators to enter the brain to increase transcribed DNA, which affects the expression of genes responsible for synaptic plasticity. Researchers used DHCA and Mal-gluc combined therapy to simultaneously suppress peripheral inflammation, regulate synaptic plasticity in the brain, and synergistically optimize performance against chronic stress depression.
 
新 These new natural grape-derived polyphenolic compounds, which target inflammation-related cellular and molecular pathways, may be an effective method for treating patients with depression and anxiety, and this situation will affect many people.
 
After years of process technology optimization and equipment adjustment, the Nanjing Shunxiang Plant can now provide high-quality dihydrocaffeic acid with a purity of more than 99%. The equipment and facilities used in the production meet environmental protection requirements and can provide the best safety Storage and transportation conditions. For details, please check the website www.sunxiangchem.com. If you are interested, please contact Tel: 025-86819868, E-mail: sales jinchemical.com.
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