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01-08 

Quality identification of di-tert-butyl dicarbonate

Di-tert-butyldicarbonateisalsoknownasBOC-anhydride,abbreviatedasDIBOCinEnglish.Itisusedtointroduceaminoacidprotectiongenesinorganicsynthesis,especiallyforaminoacidprotection.Itiswidelyusedinthesynthesisofmanyproductssuchasmedicine,proteinandpeptidesynthesis,biochemicalfood,cosmeticsandsoon.Becauseitisanintermediatesyntheticprotectiveagent,itsqualitydirectlyaffectsitseffectivenessandthequalityofdownstreamproducts. Forallusersofdi-tert-butyldicarbonate,howtoidentifythequalityoftheproductafterreceivingthegoodsisadifficultproblem. Theidentificationofhigh-qualitydi-tert-butyldicarbonateshouldbestartedfromthefollowingaspects: 1,Appearance: 外观Theappearanceofhigh-qualitydi-tert-butyldicarbonateproductshouldbecolorlesstransparentliquidorcrystal.Iftheappearanceoftheproductisslightlyyellow,itmeansthatthesolventcontentintheproductishighanditisanon-qualityproduct. 2,maincontent: 指标Thisindicatorisamust-haveitemforproductanalysissheets.Althoughtherearemanydomesticsuppliersofthisproduct,thecontentisgenerallyabove99%,andtherearefewmorehigh-qualityproducts.Themaincontentofdi-tert-butyldicarbonateproducedbyNanjingShunxiangisusuallyhigherthan99.5%,anditisdifficultforsimilarmanufacturerstomeetthisstandard. 3.Moisturecontent: Themoisturecontentofhigh-qualitydi-tert-butyldicarbonateshouldbelessthan0.01%. 4.Impurities: Thelowertheimpuritycontent,thehighertheproductpurity.Theimpuritycontentofdi-tert-butyldicarbonatesuppliedbyNanjingShunxiangisusuallylessthan0.019%,andthedi-tert-butyldicarbonateofhighpurityproductshasalmostnootherimpurities. 5.Stability: High-qualitydi-tert-butyldicarbonate,whichislessaffectedbytemperature,isnoteasytodecompose,easytotransport,andeasytostore.JinxiangChemical's8-yeardatastatistics:stableandhigh-qualityBOC-anhydride,withameltingpointof22~25℃,themaincontentdecreasedbyonly0.2~0.3%within40days. 6.Solventcomposition: WhetheritmeetsFDAsolventsafetystandards.Inthepastfewyears,JinxiangChemicalhasresearchedprocessrefinementandrepeatedtests.Intheproductionprocess,itusessolventsthatfullymeettherequirementsoftheUSFDA.Ithasproducedhigh-qualitydi-tert-butyldicarbonate.Doesnotcontainisopropylandsec-butylgroupimpurities,noheavymetalimpurities.

01-08 

Market Demand for Pyridine Hydrobromide

Pyridinehydrobromide,alsoknownaspyrimidinehydrobromide,EnglishnameisPyridinehydrobromide.Commonlyusedasaseriesofpioneermedicines,suchas:Ceftazidime,Cefpirin,Ceftazidimeandotherintermediates,andsometimesalsousedaspapermakingadditives.Itisawidelyusedpharmaceuticalintermediate. Pyridinehydrobromidebelongstothestrongacidsystem.Intheproductionprocess,theacidresistanceoftheequipmentisrelativelyhigh,andtheproductionisdifficult.Despitethis,thedemandforpyridinehydrobromideisstillverystrongregardlessofthedomesticorforeignmarket.Basedonmarketdemand,therearemoreandmoredomesticpharmaceuticalplantsproducingpyridinehydrobromide.Thereareseveralreasonsforthis. Firstofall,pyridiniumhydrobromideisanindispensablerawmaterialformakingvancomycindrugs.Pioneerindrugsaremainlyusedtofightinfections.Forexample,cefotaximeisusedforrespiratoryinfectionscausedbysensitivebacteria,skinandsofttissueinfections,urinarytractinfections,biliaryinfections,andchestandabdominalinfections.Canbeusedformeningitis,sepsis,pleurisy.Moreover,ithasaparticularlystrongeffectonEscherichiacoli.Itisusedinmanymedicinesfortreatinggastriculcerandduodenalulcer,andpyridinehydrobromideisalsousedinthenaturalpreparationofmedicines. Secondly,thedomesticsynthesisofpyridinehydrobromideisbecomingmoreandmoremature.Industrialproductionofpyridiniumhydrobromidehasbecomeamajortrend.Therawmaterialsusedintheproductionprocess,suchasaldehydes,ketones,andammonia,areallbasicchemicalrawmaterials.Theserawmaterialsareabundantindomesticsupplyandthepriceislow,whichisconducivetopyridinehydrobromide.Thesynthesisofacidsaltprovidesthebasisformassproductionofpyridinehydrobromide. Inadditiontotheabove,lowcostisalsoamajorreasonforthestrongmarketdemandforpyridinehydrobromide.Duetothecontinuousprogressoftheproductionprocess,thesynthesizedpyridiniumhydrobromideisnotonlygreenandenvironmentallyfriendly,butalsotheoperationprocessbecomesincreasinglysimple,whichgreatlysavesproductioncosts.Thismakesiteasiertoachievethegoalsoflowcostandhighoutput. 多年Afteryearsofprocesstechnologyoptimizationandequipmentadjustment,NanjingShunxiangPlantcannowprovidehigh-purity,high-qualitypyridiniumhydrobromide.TheequipmentandfacilitiesusedbyNanjingShunxianginproductionmeetenvironmentalprotectionrequirements,andcanprovidethebestandsafeststorageandtransportationconditions.Formoreinformation,pleasevisitwww.sunxiangchem.com.Ifyouareinterested,pleasecontactTel:025-86819868,E-mail:salesjinchemical.com

01-08 

Adapt to the future market and grasp the diverse applications of hydroxytyrosol

Hydroxytyrosol,alsoknownas3,4-dihydroxyphenylethanol,CASnumber10597-60-1,ismainlyfoundinoliveleaves.Thereisalsoacertaincontentinoliveoilandwastewaterfromprocessingoliveoil. Diversityofhydroxytyrosolhasbeenwidelyrecognizedinrecentyears.Firstappliedtobeautyproductsandhealthproducts,ithelpsthebodyabsorbminerals,promotesmetabolism,promoteswoundhealing,anddelaysaging. Furthermore,hydroxytyrosolcanalsopromotetherecoveryofcancerinthelaterstageandimprovetheeffectofchemotherapy.Itissuperiortosimilardrugsinthepreventionandtreatmentofarteriosclerosis,hypertensionandheartdisease,anditalsopreventsandcuresvariousdiseasescausedbysmoking. Inaddition,hydroxytyrosolisusedasanaturalantibacterial,antiviralandfungicidalproductforagricultureandpestcontrol. NanjingShunxiangPharmaceuticalresearchedalargenumberofresearchdataathomeandabroad,andconfirmedthathydroxytyrosolhasgoodbiologicalactivityinallaspects,andisafunctionalmoleculewithbroadapplicationprospects,showingitshighapplicationvalue. Intheproductionprocessofhydroxytyrosol,NanjingShunxiangMedicinehasbeencontinuouslyimprovedandoptimizedtoensurethattheproductionofhydroxytyrosolismorestable,efficientandsafer.Thehydroxytyrosolstorage,transfer,packaging,transportationandotherlinksalsohaveclearcorrespondingoperatingspecificationsandinstructionstoensurethateachusercanfinallygethigh-qualityproducts,withthebestqualityrawmaterialsintothenextproductionlink.Fordetails,pleasecheckthewebsitewww.sunxiangchem.com.Ifyouareinterested,pleasecontactTel:025-86819868,E-mail:salesjinchemical.com.

01-08 

Future prospects and uses of dihydrocaffeic acid

Dihydrocaffeicacid,alsoknownas3,4-dihydroxyphenylpropionicacid,isawhitecrystallinepowderthatissolubleinorganicsolventssuchasmethanol,ethanol,andDMSO.longituba,hasstrongantioxidantactivity. InastudypublishedonlineinthejournalNatureCommunications,scientistsdescribedanextensiveanalysisofnewgrape-derivedcompounds,dihydrocaffeicacid(DHCA),andsunflowerpigment3-O-glucoside(Mal-gluc),whichmaybeacurefordepression.Thefindingssuggestthatthesenaturalcompoundscanattenuatedepressionbytargetingnewlydiscoveredpotentialmechanisms. TheresearchersfoundthatDHCAandMal-gluccanpromotetheresilienceofdepressionmodelinmicebyregulatinginflammationandsynapticplasticity.DHCAreducesinterleukin6(IL-6),apro-inflammatorysubstancesecretedbyTcellsandmacrophages,whichstimulatestheimmuneresponsebyphenotypingthenon-codingsequencesoftheIL-6gene.Mal-glucregulatesthehistoneacetylationoftheRac1geneandallowstranscriptionalactivatorstoenterthebraintoincreasetranscribedDNA,whichaffectstheexpressionofgenesresponsibleforsynapticplasticity.ResearchersusedDHCAandMal-gluccombinedtherapytosimultaneouslysuppressperipheralinflammation,regulatesynapticplasticityinthebrain,andsynergisticallyoptimizeperformanceagainstchronicstressdepression. 新Thesenewnaturalgrape-derivedpolyphenoliccompounds,whichtargetinflammation-relatedcellularandmolecularpathways,maybeaneffectivemethodfortreatingpatientswithdepressionandanxiety,andthissituationwillaffectmanypeople. Afteryearsofprocesstechnologyoptimizationandequipmentadjustment,theNanjingShunxiangPlantcannowprovidehigh-qualitydihydrocaffeicacidwithapurityofmorethan99%.TheequipmentandfacilitiesusedintheproductionmeetenvironmentalprotectionrequirementsandcanprovidethebestsafetyStorageandtransportationconditions.Fordetails,pleasecheckthewebsitewww.sunxiangchem.com.Ifyouareinterested,pleasecontactTel:025-86819868,E-mail:salesjinchemical.com.